Simultaneous Quantitative Resolution of Atorvastatin Calcium and Fenofibrate in Pharmaceutical Preparation by Using Derivative Ratio Spectrophotometry and Chemometric Calibrations

この論文にアクセスする

この論文をさがす

著者

抄録

In the present work, five different spectrophotometric techniques for simultaneous determination of formulations containing atorvastatin calcium (ATOR) and fenofibrate (FENO) in various combinations are described. In ratio spectra derivative spectrophotometry, analytical signals were measured at wavelengths corresponding to either maximums or minimums for both drugs in first derivative spectra of ratio spectra obtained by using either spectrum as divisor. For the remaining four methods using chemometric techniques, namely, classical least squares (CLS), inverse least squares (ILS), principal component regression (PCR) and partial least squares (PLS), the calibrations were constructed by using the absorption data matrix corresponding to the concentration data matrix, with measurements in the range of 231 - 310 nm (Δ<i>λ</i> = 1 nm) in their zero-order spectra. The linearity range was found to be 4 - 22 and 2 - 20 µg/ml for ATOR and FENO, respectively. The validity of the proposed methods was successfully assessed for analyses of both drugs in laboratory-prepared mixtures and in commercial tablet formulations.

収録刊行物

  • Analytical sciences : the international journal of the Japan Society for Analytical Chemistry

    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 23(4), 445-451, 2007-04-10

    The Japan Society for Analytical Chemistry

参考文献:  49件中 1-49件 を表示

  • <no title>

    BARRETT H.

    Atherosclerosis 4(Supplement), 230, 2003

    被引用文献1件

  • <no title>

    VOJTECH M.

    Am. Heart J. 144, E6, 2002

    被引用文献1件

  • <no title>

    MILIONIS H. J.

    Am. J. Cardiol. 88, 203, 2001

    被引用文献1件

  • <no title>

    PAPAGEORGIOU A. A.

    Atherosclerosis 3(Supplement), 70, 2002

    被引用文献1件

  • <no title>

    SUPERKO R. H.

    J. Am. College Cardiol. 41, 316, 2003

    被引用文献1件

  • <no title>

    ISHIGAMI M.

    Atherosclerosis 4(Supplement), 161, 2003

    被引用文献1件

  • <no title>

    MALIK J.

    Cardiovasc. Res. 52, 290, 2001

    被引用文献1件

  • <no title>

    SIDIKA E.

    J. Pharm. Biomed. Anal. 33, 1017, 2003

    被引用文献1件

  • <no title>

    GHOLAMREZA B.

    J. Chromatogr., B 826, 41, 2005

    被引用文献1件

  • <no title>

    NEVIN E.

    Crit. Rev. Anal. Chem. 34, 1, 2004

    被引用文献1件

  • <no title>

    EL-GINDY A.

    Il Farmaco 60, 425, 2005

    被引用文献1件

  • <no title>

    JI X.

    Zhongguo Yaoke Daxue Xucbao 18, 284, 1987

    被引用文献1件

  • <no title>

    PAULINE L. M.

    J. Pharm. Biomed. Anal. 18, 383, 1998

    被引用文献1件

  • <no title>

    FAN G. R.

    Yaowu Fenxi Zazhi 20, 231, 2000

    被引用文献1件

  • <no title>

    ABBASPOUR A.

    J. Pharm. Biomed. Anal. 38, 420, 2005

    被引用文献1件

  • <no title>

    ERDAL D.

    J. Pharm. Biomed. Anal. 30, 715, 2002

    被引用文献1件

  • <no title>

    MURAT P.

    J. Pharm. Biomed. Anal. 34, 473, 2004

    被引用文献1件

  • <no title>

    ERDAL D.

    J. Pharm. Biomed. Anal. 28, 591, 2002

    被引用文献1件

  • <no title>

    ERDAL D.

    Il Farmaco 58, 1151, 2003

    被引用文献1件

  • <no title>

    ERDAL D.

    Anal. Lett. 37, 679, 2004

    被引用文献1件

  • <no title>

    MARIA C. S.

    Anal. Lett. 34, 363, 2001

    被引用文献1件

  • <no title>

    GARRIDO F. A.

    J. Chromatogr., A 727, 27, 1996

    被引用文献1件

  • <no title>

    ROSANGELA B. C.

    J. Pharm. Biomed. Anal. 38, 94, 2005

    被引用文献1件

  • <no title>

    MARTENS H.

    Multivariate Calibration, 1989

    被引用文献1件

  • <no title>

    KRAMER R.

    Chemometric Techniques in Quantitative Analysis, 1998

    被引用文献1件

  • <no title>

    ADAMS M. J.

    Chemometrics in Analytical Spectroscopy, 1995

    被引用文献1件

  • <no title>

    WOLD S.

    The Multivariate Calibration Problem in Chem Solved by PLS, 1983

    被引用文献1件

  • <no title>

    STONE M.

    J. Roy. Stat. Soc. B. 36, 111, 1974

    被引用文献1件

  • <no title>

    BECKER R. A.

    The New S Language, 1988

    被引用文献1件

  • Effect of atorvastatin and fenofibrate on autonomic tone in subjects with combined hyperlipidemia

    MELENOVSKY V.

    Am J Cardiol 92, 337-341, 2003

    DOI 被引用文献2件

  • <no title>

    MANN E. E.

    J. Liq. Chromatogr. Relat. Technol. 20, 2441, 1997

    被引用文献1件

  • <no title>

    ERK N.

    Anal. Lett. 36, 2699, 2003

    被引用文献1件

  • <no title>

    BULLEN W. W.

    J. Am. Soc. Mass Spectrom. 10, 55, 1999

    被引用文献8件

  • <no title>

    JEMAL M.

    Rapid Commun. Mass Spectrom. 13, 1003, 1999

    被引用文献7件

  • <no title>

    SHUM Y. Y.

    Ther. Drug Monit. 20, 41, 1998

    被引用文献1件

  • <no title>

    YARDIMCI C.

    Anal. Bioanal. Chem. 378, 495, 2004

    DOI 被引用文献1件

  • <no title>

    SALINAS F.

    Talanta 37, 347-351, 1990

    被引用文献3件

  • <no title>

    GARCIA M. D. G.

    Anal. Chim. Acta 348, 177, 1997

    被引用文献1件

  • <no title>

    HERRERO A.

    Anal. Chim. Acta 348, 51, 1997

    被引用文献2件

  • <no title>

    HAALAND D. M.

    Anal. Chem. 60, 1193, 1988

    被引用文献10件

  • <no title>

    BEEBE K. R.

    Anal. Chem. 59, 1007A, 1987

    被引用文献1件

  • <no title>

    FRANS S. D.

    Anal. Chem. 57, 2680, 1985

    被引用文献1件

  • <no title>

    THOMAS E. V.

    Anal. Chem. 66, 795A, 1994

    被引用文献1件

  • Partial least-squares regression : a tutorial

    GELADI P.

    Anal Chim Acta 185, 1-17, 1986

    DOI 被引用文献21件

  • <no title>

    COWE I. A.

    Analyst 110, 1233, 1985

    被引用文献2件

  • <no title>

    BRERETON R. G.

    Analyst 125, 2125-2154, 2000

    被引用文献3件

  • <no title>

    MARTINEZ L. L.

    Anal. Chim. Acta 493, 83, 2003

    DOI 被引用文献1件

  • <no title>

    NAES T.

    J. Chemometrics 2, 155, 1988

    被引用文献1件

  • <no title>

    MILLER J. N.

    Analyst 116, 3-14, 1991

    被引用文献7件

各種コード

  • NII論文ID(NAID)
    10018914318
  • NII書誌ID(NCID)
    AA10500785
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    09106340
  • NDL 記事登録ID
    8698560
  • NDL 雑誌分類
    ZP4(科学技術--化学・化学工業--分析化学)
  • NDL 請求記号
    Z54-F482
  • データ提供元
    CJP書誌  NDL  J-STAGE 
ページトップへ