Pseudomenbranous Colitis after Orthopedic Surgery

  • Hara Katsutoshi
    Department of Orthopedic Surgery, Faculty of Medicine, Oita University, Oita, Japan
  • Kaku Nobuhiro
    Department of Orthopedic Surgery, Faculty of Medicine, Oita University, Oita, Japan
  • Tsumura Hiroshi
    Department of Orthopedic Surgery, Faculty of Medicine, Oita University, Oita, Japan

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Other Title
  • 整形外科術後に発症した偽膜性腸炎

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Abstract

It is important to prevent surgical site infection in patients using antibiotics, which however may cause certain postoperative problems themselves. We report 14 patients who developed pseudomenbranous colitis after orthopedic surgery from 1996 to 2005. They consisted of five men and nine women, with a mean age of 64.4 years. One patient was treated with cessation of antibiotics alone, and other patients were placed in oral vancomycin in addition to it. A mean duration of 4.9 days was spent from initiation of antibiotics to onset of symptoms, and a mean duration of 3.4 days was required between onset of symptoms and diagnosis of pseudomembranous colitis. Diarrhea improved in five patients within one week, however, five patients required treatment for a period of one month or more. Although one patient had to undergo abdominal surgery for treatment but, she died one month after orthopedic surgery. As perioperative antibiotic therapy may sometimes cause pseudomembranous colitis, general conditions and symptoms of colitis must be carefully monitored, and efforts made for immediate and appropriate diagnosis and treatment.

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