好酸球性膿疱性毛嚢炎の2例  [in Japanese] Two Cases of Eosinophilic Pustular Folliculitis  [in Japanese]

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Abstract

好酸球性膿疱性毛嚢炎の2症例を報告した。症例1は62歳女性。シェーグレン症候群を思わせる顔面の環状の紅斑。自覚症状はなかった。生検にて毛嚢への好酸球の浸潤と毛嚢の変性像を認めた。インドメタシン内服に反応せず,背部にも同様の紅斑が出現した。症例2は25歳女性。顔面のそう痒を伴う環状の紅斑。トシル酸スプラタストの2週間の内服により消失し,再燃を認めず。臨床像および治療に関して特異的と思われた2例と当科過去7年間に経験した3例を簡単に報告し,若干の文献的考察を加えた。

We report two cases of eosinophilic pustular folliculitis. Case 1. The patient was a 62-year-old woman. She noticed an annular erythema with no pruritus, follicular papules, pustules, or scales on her left cheek about 1 month prior to presentation. In November 2000, she was referred to our department. Histopathologically, there were numerous eosinophils which infiltrated in the perifollicles and hair follicles. In spite of the oral administration of indometacin (50∼75mg per day), the annular erythema continued to grow in size. Case 2. The patient was a 25-year-old woman, she developed follicular papules and very pruritic annular erythema on the left cheek one month prior to admission. In May 1995, she was referred to our department. Histopathologically, there were numerous eosinophils which infiltrated into the hair follicles. After the oral administration of suplatast tosilate (300mg per day), her skin lesions rapidly disappeared and did not recur even after discontinuing the medication. The clinical features and treatments of there two cases are very interesting and differ from those previously reported.

Journal

  • The Nishinihon Jourrnal of Dermatology  

    The Nishinihon Jourrnal of Dermatology 64(2), 173-177, 2002-04-01 

    Western Division of Japanese Dermatological Association

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