A Case with Cryoglobulin-positive Chronic Hepatitis C and Erythematosus-like Eruptions.

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  • エリテマトーデスと鑑別を要したクリオグロブリン陽性,慢性C型肝炎の1例

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Abstract

A 72-year-old woman with chronic hepatitis C and cryoglobulinaemia developed various cutaneous manifestations. The patient exhibited erythema, mimicking a butterfly rash of erythematosus on her face, pruritic red plaques on the back of her hands and forearms, and livedo reticularis and purpura on the extremities after being exposed to the cold for one month. Laboratory examinations revealed negative antinuclear antibody, low CH50, high γ-globulin, elevated GOT and GPT levels, mixed cryoglobulinaemia, and positive hepatitis C antibodies. The cryoglobulinaemia was identified as Type III. A skin biopsy from the pruritic red plaques on the left forearm showed lichenoid tissue reactions. Her cutaneous manifestations improved after being treated for chronic hepatitis C. The present case suggests that the development of various cutaneous manifestations may thus be associated with hepatitis C virus infection.

Journal

  • Nishi Nihon Hifuka

    Nishi Nihon Hifuka 64 (4), 419-422, 2002

    Western Division of Japanese Dermatological Association

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