フチン酸により Sentinel Node を同定した足趾原発皮膚悪性腫瘍の2例  [in Japanese] Successful Mapping of Sentinel Lymph Nodes with Technetium-99m Phytate in Two Cases with Cutaneous Malignancies Arising on a Toe  [in Japanese]

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Author(s)

    • 山崎 修 YAMASAKI Osamu
    • 岡山大学大学院医歯学総合研究科皮膚・粘膜・結合織学 Department of Dermatology, Okayama University Graduate School of Medicine and Dentistry
    • 浅越 健治 ASAGOE Kenji
    • 岡山大学大学院医歯学総合研究科皮膚・粘膜・結合織学 Department of Dermatology, Okayama University Graduate School of Medicine and Dentistry
    • 牧野 英一 MAKINO Eiichi
    • 岡山大学大学院医歯学総合研究科皮膚・粘膜・結合織学 Department of Dermatology, Okayama University Graduate School of Medicine and Dentistry
    • 岩月 啓氏 IWATSUKI Keiji
    • 岡山大学大学院医歯学総合研究科皮膚・粘膜・結合織学 Department of Dermatology, Okayama University Graduate School of Medicine and Dentistry
    • 佐藤 修平 SATO Shuhei
    • 岡山大学大学院医歯学総合研究科放射線医学 Department of Radiology, Okayama University Graduate School of Medicine and Dentistry
    • 平木 祥夫 HIRAKI Yoshio
    • 岡山大学大学院医歯学総合研究科放射線医学 Department of Radiology, Okayama University Graduate School of Medicine and Dentistry

Abstract

<sup>99m</sup>テクネシウムフチン酸によるリンパシンチグラフィを施行した足趾原発皮膚悪性腫瘍の2例を報告した。症例1は67歳男性の右1趾爪部の悪性黒色腫。<sup>99m</sup>テクネシウムスズコロイドによるリンパシンチグラフィではリンパ節は描出されず,<sup>99m</sup>テクネシウムフチン酸にて右鼠径に2個の高集積するリンパ節が描出された。症例2は61歳男性の右1趾爪部の有棘細胞癌。<sup>99m</sup>テクネシウムフチン酸によるリンパシンチグラフィにて3個の高集積するリンパ節が描出された。それぞれ術中の色素法を併用しsentinel nodeと同定し摘出した。<sup>99m</sup>テクネシウムフチン酸は<sup>99m</sup>テクネシウムスズコロイドに比し粒子径が小さく,特に足趾など粒子がリンパ行路に移行しにくい末端部では有用な核種と思われた。

We herein report the successful usage of preoperative lymphoscintigraphy using technetium-99 m-phytate for two cases of cutaneous malignancies arising in a toe. Case 1 was a 67-year-old man with subungual melanoma on his right big toe. Although no sentinel nodes were detected by lymphoscintigraphy using technetium-99 m tin colloid, technetium-99 m phytate successfully demonstrated two sentinel nodes in the right inguinal region. Case 2 was a 61-year-old man with subungual squamous cell carcinoma on his right big toe. Lymphoscintigraphy using technetium-99 m phytate demonstrated three sentinel nodes in the right inguinal region. The sentinel nodes imaged by lymphoscintigraphy were further identified using intraoperative blue dye and then were successfully excised in both cases. Because phytate is smaller in size than tin colloid, technetium-99 m phytate is thus considered to be potentially useful for the detection of sentinel nodes.

Journal

  • The Nishinihon Jourrnal of Dermatology  

    The Nishinihon Jourrnal of Dermatology 64(4), 439-442, 2002-08-01 

    Western Division of Japanese Dermatological Association

References:  10

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