セレニウムおよびビタミンE剤投与が周産期乳牛のリンパ球幼若化能に及ぼす影響  [in Japanese] Effect of E-SE Injection on Lymphocyte Blastogenesis in Cows at Periparturient Period  [in Japanese]

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Author(s)

Abstract

分娩前3週の乳牛にセレニウム (Se)-ビタミンE (VE) 製剤 (E-SE剤, Seとして25mgおよびVEとして680IU) を1回筋肉内投与し, 分娩前後の血清SeおよびVE濃度と末梢血液リンパ球幼若化能の推移を検討した.E-SE剤投与牛の血清Se濃度は, 分娩時および分娩後1週には対照牛に比べ有意な高値を示した. 投与牛のリンパ球幼若化能は, 分娩時には分娩前に比べ低値を示したが, 以降分娩後4週までは対照牛に比べ高値で推移し, 特に, 分娩後1週 (Con A, PWM), 2週および4週 (PHA) には対照牛に比べ有意な高値を示した. 乳牛に対する分娩前3週のE-SE剤投与は, 分娩にともなって低下するリンパ球幼若化能の回復を早める作用があるものと考えられた.

The mitogenic responses of peripheral blood lymphocytes were investigated in the cows after a single intramuscular injection of E-SE (selenium; 25mg and vitamin E; 680IU) at 3 weeks before parturition. In the E-SE injected cows, the serum concentration of selenium was significantly higher than those in the control cows at parturition and 1 week after parturition. The mitogenic response in injected cows was significantly higher than that in the control cows at 1 week after parturition for concanavalin A (Con A) and pokeweed mitogen (PWM), and at 2 and 4 weeks after parturition for phytohaemagglutinin (PHA). A single intramuscular injection of E-SE at 3 weeks before parturition might be related to the recovery ofimpaired lymphocyte blastogenesis in the cows at periparturient period.

Journal

  • Journal of the Japan Veterinary Medical Association  

    Journal of the Japan Veterinary Medical Association 49(9), 619-622, 1996-09-20 

    Japan Veterinary Medical Association

References:  24

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Codes

  • NII Article ID (NAID)
    10018940972
  • NII NACSIS-CAT ID (NCID)
    AN00191857
  • Text Lang
    JPN
  • Article Type
    SHO
  • ISSN
    04466454
  • NDL Article ID
    4068819
  • NDL Source Classification
    ZR22(科学技術--農林水産--畜産)
  • NDL Call No.
    Z18-352
  • Data Source
    CJP  NDL  IR  J-STAGE 
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