タバコ副流煙の粒子状およびガス・蒸気状物質の変異原性  [in Japanese] Mutagenicity of the Particular, Gaseous and Vaporus Substances of Cigarette Side-Stream  [in Japanese]

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Abstract

タバコ副流煙中に含まれる粒子状およびガス・蒸気状物質の変異原性を, Ames法およびガス曝露法で検討したところ, 粒子状物質は供試全菌株 (<I>Escherichia coli</I>WP2uvrA/pKM101, <I>Salmonella typhimurium</I>TA100およびTA98) に対して変異原性を示したが, ガス・蒸気状物質は<I>Salmonella typhimurium</I>TA98に対して変異原性を示さなかった.<BR>S. typhimuriumTA100株に対する変異原性は粒子状物質とガス・蒸気状物質との間に差はなかったが, <I>Escherichia coli</I>WP2uvrA pKM101株に対してはガス・蒸気状物質の変異原性は5~10倍高かった.

Particular, gaseous and vaporus substances of cigarette side-stream smoke were investigated for mutagenicity by the Ames preincubation and gas exposure systems. Particulates were mutagenic for in the<I>Escherichia</I>coli WP 2uvrA/pKM 101 and<I>Salmonella typhimurium</I>TA 100 and TA 98, while gaseous and vaporus substances were not for<I>S. typhimurium</I>TA 98. There was no difference in mutagenicity for<I>S. typhimurium</I>TA 100 between gaseous or vaporus substances and particulates, but the mutagenicity of gaseous and vaporous substances for<I>E. coli</I>WP 2uvrA/pKM 101 was 5 to 10 times higher than that of particulate.

Journal

  • Journal of the Japan Veterinary Medical Association  

    Journal of the Japan Veterinary Medical Association 49(9), 661-665, 1996-09-20 

    Japan Veterinary Medical Association

References:  21

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Codes

  • NII Article ID (NAID)
    10018941052
  • NII NACSIS-CAT ID (NCID)
    AN00191857
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    04466454
  • NDL Article ID
    4068825
  • NDL Source Classification
    ZR22(科学技術--農林水産--畜産)
  • NDL Call No.
    Z18-352
  • Data Source
    CJP  CJPref  NDL  J-STAGE 
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