Pyrogenic Effect of Culture Filtrate of<I>Campylobacter jejuni</I>

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  • <I>Campylobacter jejuni</I>培養ろ液の発熱性
  • Campylobacter jejuni培養ろ液の発熱性
  • Campylobacter jejuni バイヨウロエキ ノ ハツネッセイ
  • Pyrogenic Effect of Culture Filtrate ofCampylobacter jejuni

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Abstract

Two strains ofCampylobacter jejuniisolated from a human sporadic diarrhea case and a healthy cow were examined to clarify the quantity of endotoxin production and pyrogenicity to rabbits. Both strains were grown microaerobically in brain heart infusion broth at 42°Cfor 7 days. These culture supernatants filtered through 0.45 and 0.20μm-filter after centrifugation were endotoxin-positive in the Limulus test at a dilution of 106. And the minimum pyrogenic dose which elicits a rise in temperature of 0.6°Cin rabbits, was 1ml/kg administration of 102diluted sample with both strains.

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