豚のクマリン中毒  [in Japanese] Coumarin Poisoning in Pigs  [in Japanese]

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Abstract

肥育豚15頭 (110~115日齢) が, 破行, 眼球突出, 関節の腫脹を呈し, そのうち6頭が死亡した.剖検では, 眼窩, 頸部, 上腕部, 内股部, 四肢肢端に出血と凝固不全の血塊を認め, 病理組織所見では筋膜下および筋間の出血が著明であった. クマリン系殺鼠剤の中毒が疑われ, 中毒物質であるクマテトラリルを高速液体クロマトグラフィーで分析したところ, 死亡豚の肝臓から0.7~0.8ppm, 腎臓からは0.1ppmのクマテトラリルが検出され, クマリン中毒と確定診断した.

Fifteen fattening (110-115 day-old) pigs presented with exophthalmos, articular swelling, and lameness and 6 of them died. At necropsy, hemorrhage with hypocoagulable clots was seen at the orbital, cervical, brachial and inner thigh regions and extremities. Histopathologically, remarkable subfascial and intermuscular hemorrhage was observed. By high performance liquid chromatography, 0.7 to 0.8ppm and 0.1ppm of coumatetralyl were detected from the liver and kidneys of dead cases, respectively. From these results, the coumarin poisoning was con firmed.

Journal

  • Journal of the Japan Veterinary Medical Association  

    Journal of the Japan Veterinary Medical Association 48(1), 18-20, 1995-01-20 

    Japan Veterinary Medical Association

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Codes

  • NII Article ID (NAID)
    10018944212
  • NII NACSIS-CAT ID (NCID)
    AN00191857
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    04466454
  • NDL Article ID
    3909386
  • NDL Source Classification
    RB84(畜産--家畜--豚)
  • NDL Source Classification
    ZR22(科学技術--農林水産--畜産)
  • NDL Call No.
    Z18-352
  • Data Source
    CJP  CJPref  NDL  IR  J-STAGE 
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