Optimal Time of Initial Administration of Live Vaccine for Infectious Burasal Disease in Chicks with Maternally Derived Antibody

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  • 移行抗体保有ひなにおける伝染性ファブリキウス嚢病生ワクチン (ひな用) の投与適期
  • イコウ コウタイ ホユウヒ ナニ オケル デンセンセイ ファブリキウスノウビョ

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Abstract

The optimal time of initial vaccination with a mild-type live IBD vaccine in chicks with maternally derived antibody (MDA) was studied. The half-life of MDA was 3.46 days, and critical MDA titer to protect from infection with field virus was 1: 28. The protective immunity was acquired 6 days after vaccination, and an MDA titer of 1: 28 interfered with active immunization. If the initial vaccination should be made at age when geometric mean MDA titer lowered to 1: 80, the optimal time (Y) was calculated from age of MDA titration in days (Z) and log10 geometric mean MDA titer (X) of flocks by the following formula; Y=11.49X+Z-21.87.

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