スルファモノメトキシンおよびオルメトプリム合剤による肥育牛コクシジウム症の治療  [in Japanese] Effects of Sulfamonomethoxine Combined with Ormetoprim on Bovine Coccidiosis  [in Japanese]

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Abstract

コクシジウム<I>Eimeria zuernii</I>および<I>E. bovis</I>オーシスト排泄が認められた肥育牛 (アバデーン・アンガス種F1, 4.6~17.3ヵ月齢;29頭は1歳以上) 32頭を3群にわけ, 2群にはスルファモノメトキシン (SM) およびオルメトプリム (OR) の合剤10mg (SM 7.5mg+OR 2.5mg)/kg/日, あるいは20mg (SM 15mg+OR 5mg)/kg/日を3または5日間連続投与し, 他の1群にはSM剤 (30mg/kg/日) を単独投与した. 投薬後3または7日で62.5~66.7%の牛で下痢が治癒したが, 3群間に有意差はなく, OPG値はいずれの群においても顕著に減少した (p<0.01またはp<0.05).SM 15mg+OR 5mg/kg投与群は最高値 (95.8%) を示したが, OPG減少率に有意差は認められなかった.

Thirty-two beef cattle (Abaerdeen Angus F1) aged 4.6 to 17.3 months, mostly more than one-year-old excreting <I>Eimeria zuernii</I> or <I>E. bovis</I> oocysts in feces, were devided into 3 groups, and one of them was treated with sulfamonomethoxine (SM) 7.5mg and ormetoprim (OR) 2.5mg/kg/day for 3 or 5 consecutive days, while another with SM 15mg+OR 5mg/kg/day. The remaining one group served as control given SM alone (30mg/kg/day). Following the drug administration 62.5 to 66.7% cattle showed the improved symptoms, and the recovery of the diarrhea was observed 3 or 7days after treating, but no significant difference was not seen among the 3 groups. The OPG values were also reduced obviously (p<0.01 or p<0.05) in each group, but there was no significant difference in the number of oocysts excreted in feces among the groups. The rate of decrease in number of oocysts was most remarkable (95.8%) in those given 15mg SM+5mg OR.

Journal

  • Journal of the Japan Veterinary Medical Association  

    Journal of the Japan Veterinary Medical Association 51(10), 579-582, 1998-10-20 

    Japan Veterinary Medical Association

References:  21

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Codes

  • NII Article ID (NAID)
    10018948374
  • NII NACSIS-CAT ID (NCID)
    AN00191857
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    04466454
  • NDL Article ID
    4578283
  • NDL Source Classification
    ZR22(科学技術--農林水産--畜産)
  • NDL Call No.
    Z18-352
  • Data Source
    CJP  CJPref  NDL  IR  J-STAGE 
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