Detection of Anti-nuclear Antibodies in Diseased Dogs

• INOKUMA Hisashi

  Faculty of Agriculture, Yamaguchi University

• YAMANE Mutsuko

  Faculty of Agriculture, Yamaguchi University

• ONISHI Takafumi

  Faculty of Agriculture, Yamaguchi University

• NISHIDA Koji

  メディカルセンター西田

Bibliographic Information

Other Title

• 各種疾患犬における抗核抗体の検出
• カクシュ シッカンケン ニ オケル コウカク コウタイ ノ ケンシュツ

Abstract

One hundred and seventy-two healthy and 197 diseased dogs were examined for anti-nuclear antibodies (ANA) by indirect immunofluorescence using feline kidney cell culture (CRFK). While all the healthy dogs showed ANA titers lower than 1: 40, some of the diseased dogs showed ANA titers of 1: 40 or higher; one of 8 cases with endocrine diseases, 1 case with systemic lupus erythematodes-like disease, 1 of 25 cases with immunemediated disease or allergy, 7 of 47 cases with neoplasia, 2 of 28 cases with bacterial or viral infection, 2 of 25 cases with parasitic infection, and 1 of 63 others. Strongly positive samples were also examined with other cell lines HmLu, MDCK and Hep 2, suggesting that there might be false negative cases using only a single cell line.

Journal

• Journal of the Japan Veterinary Medical Association

  Journal of the Japan Veterinary Medical Association 51 (1), 23-26, 1998

  Japan Veterinary Medical Association

Keywords

• anti-nuclear antibody
• dog
• indirect immunofluorescence

Details

• CRID: 1390001204708547584
• NII Article ID: 130004051866
• NII Article ID: 10018949616
• NII Book ID: AN00191857
• DOI: 10.12935/jvma1951.51.23
• ISSN: 21860211
• ISSN: 04466454
• NDL BIB ID: 4393378
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I4393378
• Web Site: https://search.jamas.or.jp/link/ui/1998128377
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed