Effect of Chlormadinone Acetate Treatment on Canine Prostatic Hyperplasia

• KOJIMA Yoshihiko

  Kojima Animal Hospital

• KAWAKAMI Shizuo

  麻布大学獣医学部

• SHINO Masao

  麻布大学獣医学部

Bibliographic Information

Other Title

• 犬の前立腺肥大症に対する酢酸クロルマジノンの治療効果
• イヌ ノ ゼンリツセン ヒダイショウ ニ タイスル サクサン クロルマジノン

Abstract

Dogs with prostatic hyperplasia were treated with either oral administration or subcutaneous implantation of chlormadinone acetate (CMA). In 4 orally treated (1-2mg/kg/day for 9 to 35 days) cases blood CMA levels increased to 94 to 280ng/ml immediately after starting the treatment, decreasing shortly after stopping administration. In 5 cases given CMA implantation (10mg) blood levels were maintained below 10ng/ml for a year or longer. In all treated cases the prostate decreased in size and most clinical signs disappeared. The blood cortisol and progesterone levels decreased immediately after starting the treatment, while no remarkable changes were observed on testosterone and estradiol levels.

Journal

• Journal of the Japan Veterinary Medical Association

  Journal of the Japan Veterinary Medical Association 50 (12), 725-728, 1997

  Japan Veterinary Medical Association

Keywords

• chlormadinone acetate implant
• dog
• prostatic hyperplasia

Details

• CRID: 1390282679686222848
• NII Article ID: 130004051818
• NII Article ID: 10018949898
• NII Book ID: AN00191857
• DOI: 10.12935/jvma1951.50.725
• COI: 1:CAS:528:DyaK1cXmslKgsg%3D%3D
• ISSN: 21860211
• ISSN: 04466454
• NDL BIB ID: 4381390
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I4381390
• Web Site: https://search.jamas.or.jp/link/ui/1998121978
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed