Combination of Continuous Intravenous Infusion Anesthesia of Guaifenesin-Ketamine-Xylazine and Sevoflurane Anesthesia in Horses

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  • 馬におけるグアイフェネシ-ケタミ-キシラジン持続点滴麻酔とセボプルラン麻酔の併用
  • 馬におけるグアイフェネシンーケタミンーキシラジン持続点滴麻酔とセボフルラン麻酔の併用
  • ウマ ニ オケル グアイフェネシン ケタミン キシラジン ジゾク テンテキ マ

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Abstract

Of 10 thoroughbred horses premedicated and anesthetized with intravenous injections of 1.1mg/kg xylazine, 50g guaifenesin and 2.5g sodium thiopental, 5 were subjected to general anesthesia maintained with oxygen-sevoflurane (OS) inhalation while the remaining 5 with OS anesthesia combined with continuous intravenous infusion of a mixture of 12.5 mg/ml guaifenesin-0.5mg/ml ketamine-0.125mg/ml xylazine at an infusion rate 2.4ml/kg/hr (GKX-OS). The mean durations of general anesthesia were 151min (120-190min) with OS and 173min (125-250min) with GKX-OS. End-expiratory sevoflurane concentrations during surgery ranged from 2.3 to 3.0% and from 1.5 to 2.1% in OS and GKX-OS anesthesia, respectively. Respiratory rate and arterial blood pressure were comparatively higher with GKX-OS than OS, with smooth recovery (Score 4-5) in both cases. The time required for standing-up ranged from 23 to 36min and from 30 to 45 min in OS and GKX-OS anesthesia, respectively. GKX-OS anesthesia is thought to be useful in equine practices.

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