Occurrence of the Uric Acid Stone in Newborn Piglets

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  • 新生子豚の尿酸結石の発生
  • シンセイ コブタ ノ ニョウサン ケッセキ ノ ハッセイ

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Abstract

Occurrence, structure and chemical composition of uric acid stones were examined in 269 newborn piglets before 18 days of age, which died or were killed for poor prognosis from June 1994 to May 1995. The stones were detected in 45 of 269 piglets (16.7%) at autopsy, at higher rates in April (39%), May (31%) and November (40%), while at lower rates in July (3%), August (9%) and September (8%). The highest occurrence rate (35.3%) was at 4 days of age, and 27 of 147 (18.4%) females and 18 heads of 122 (14.8%) males were shown to have stones. Nine stone samples were chemically analyzed, revealing six samples of uric acid and the other three of potassium urate. Scanning electron microscopy showed calculi 5 to 100μm in diameter and needle-like crys-tals surrounded by several shell layers.

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