口底部に発生した basaloid squamous cell carcinoma の1例 : Ki-67を用いた免疫組織化学的検索による細胞増殖能の評価 A case of basaloid squamous cell carcinoma of the floor of the mouth : Estimation of proliferative activity by Ki-67 immunohistochemical staining

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著者

    • 津野 宏彰 TSUNO Hiroaki
    • 富山医科薬科大学医学部歯科口腔外科学講座 Department of Oral and Maxillofacial Surgery, Toyama Medical and Pharmaceutical University
    • 和田 重人 WADA Shigehito
    • 富山医科薬科大学医学部歯科口腔外科学講座 Department of Oral and Maxillofacial Surgery, Toyama Medical and Pharmaceutical University
    • 井上 さやか INOUE Sayaka
    • 富山医科薬科大学医学部歯科口腔外科学講座 Department of Oral and Maxillofacial Surgery, Toyama Medical and Pharmaceutical University
    • 姚 立 YAO Li
    • 富山医科薬科大学医学部歯科口腔外科学講座 Department of Oral and Maxillofacial Surgery, Toyama Medical and Pharmaceutical University
    • 古田 勲 FURUTA Isao
    • 富山医科薬科大学医学部歯科口腔外科学講座 Department of Oral and Maxillofacial Surgery, Toyama Medical and Pharmaceutical University

抄録

Basaloid squamous cell carcinoma was first reported by Wain et al. in 1986 and has recently been designated a variant of squamous cell carcinoma because of its high potential for distant metastasis. We report a case of basaloid squamous cell carcinoma arising in the floor of the mouth in a 74-year-old man. The proliferative activities of this case and another case previously reported by our department were compared with those of 21 cases of poorly differentiated squamous cell carcinoma. The cases of basaloid squamous cell carcinoma showed high reactivity on Ki-67 immunohistochemical staining. This finding reflects the high malignancy of this disease and suggests that Ki-67 immunohistochemical staining is useful for diagnosis. Radiotherapy was very effective against the primary lesion in our two cases, but both had lung metastasis. In our patient, lung lesions were controlled by chemotherapy, but further investigations are needed to establish standard treatment, including systemic chemotherapy.

収録刊行物

  • 日本口腔外科学会雑誌  

    日本口腔外科学会雑誌 51(12), 614-617, 2005-12-20 

    Japanese Society of Oral and Maxillofacial Surgeons

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各種コード

  • NII論文ID(NAID)
    10018954120
  • NII書誌ID(NCID)
    AN00189163
  • 本文言語コード
    JPN
  • 資料種別
    NOT
  • ISSN
    00215163
  • NDL 記事登録ID
    7785391
  • NDL 雑誌分類
    ZS44(科学技術--医学--歯科学・口腔外科学)
  • NDL 請求記号
    Z19-145
  • データ提供元
    CJP書誌  CJP引用  NDL  J-STAGE 
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