口蓋に発生した mucinous adenocarcinoma の1例 A case of mucinous adenocarcinoma arising in the palate
Mucinous adenocarcinoma is a rare malignant neoplasm included in the classification of salivary gland tumors by the WHO (1991). We report a case of mucinous adenocarcinoma arising in the hard palate. A 55-yearold man was referred to our hospital because of a painless swelling in the left side of the hard palate, which was first noticed about 2 months ago and had gradually increased in size. On initial examination, an elastic hard mass measuring approximately 7×6mm in diameter with indurations was palpable. Magnetic resonance imaging showed low signals on Tl-weighted images and high signals on T2-weighted images. An internal structure was mottled on T2-weigted images. The lesion was suspected to be a malignant salivary gland tumor on biopsy. The tumor was excised with left partial maxillectomy. Microscopically, the tumor was composed of nests, glands, and cords and had a cystic structure. Mucus-filled cystic cavities were lined by tumor cells, with some floating tumor cells. The tumor cells and cystic spaces were positive for mucicarmine and PAS. Immunohistochemically, pan-keratin, CK7, vimentin, and GFAP were positive in the tumor cells. The final histopathological diagnosis was mucinous adenocarcinoma.
日本口腔外科学会雑誌 51(11), 555-558, 2005-11-20
Japanese Society of Oral and Maxillofacial Surgeons