軟口蓋の難治性潰瘍を契機に発見されたATLの1例 A case of adult T-cell leukemia with ulceration of the soft palate as an early symptom
A case of chronic type adult T-cell leukemia (ATL) with initial oral lesions in a 68-year-old woman is reported. She was referred to us because of ulceration of the left side of the soft palate and had difficulty in swallowing due to severe contact pain. The initial clinical diagnosis was severe ulcerative stomatitis. After treatment, herpetic stomatitis was followed by a fever and general weakness. Immunological blood examinations revealed positive anti-ATL, abnormal T lymphocytes (so-called flower cells), and the polyclonal integration of human T-cell leukemia virus type 1 (HTLV-1) provirus DNA. At this time, ATL was diagnosed. The initial oral lesions were subsequently thought to be an initial symptom closely associated with immune suppression caused by ATL.
日本口腔外科学会雑誌 51(10), 516-519, 2005-10-20
Japanese Society of Oral and Maxillofacial Surgeons