A case of multiple carcinoma arising in both maxillary sinuses

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  • SATOH Akira
    Oral Diagnosis and Medicine, Department of Oral Pathobiological Science, Hokkaido University Graduate School of Dental Medicine
  • KANETA Hiroyuki
    Oral Diagnosis and Medicine, Department of Oral Pathobiological Science, Hokkaido University Graduate School of Dental Medicine
  • HEMMI Tohru
    Oral Diagnosis and Medicine, Department of Oral Pathobiological Science, Hokkaido University Graduate School of Dental Medicine
  • NOTANI Ken-ichi
    Oral Diagnosis and Medicine, Department of Oral Pathobiological Science, Hokkaido University Graduate School of Dental Medicine
  • KOHGO Takao
    Laboratory of Pathology, Department of Oral Pathobiological Science, Hokkaido University Graduate School of Dental Medicine

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Other Title
  • 組織型の異なる両側異時性上顎洞癌の１例
  • ショウレイ ホウコク ソシキガタ ノ コトナル リョウソクイジセイ ジョウガクドウガン ノ 1レイ

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Abstract

We report a rare case of bilateral carcinomas of the maxillary sinuses. In 1987, the patient received irradiation therapy (60Co 50.4Gy) and partial maxillectomy for left maxillary squamous cell carcinoma (SCC, T3NOMO). Because of tumor recurrence in the left cheek 2 months after operation, he received excision of the tumor and had been free from tumor for 16 years thereafter. In 2003, he was referred to our clinic because of diffuse swelling, hypoesthesia of the right cheek, and the induration of the right upper gingiva and buccal mucous membrane. A biopsy specimen was histologically diagnosed as mucoepidermoid carcinoma, and he received chemoradiation (40Gy/20fr and TXT 18mg×3, CDDP 7.2mg×10), followed by subtotal maxillectomy and microvascular reconstruction with a free rectus abdominis muscle flap. To our knowledge, this is the second case of bilateral maxillary cancers (SCC and mucoepidermoid carcinoma) to be reported in Japan.

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