遺伝性血管神経性浮腫の1例 : 周術期管理を中心に A case of hereditary angioedema : special reference to perioperative management
Hereditary angioedema (HAE) is a rare hereditary disease caused by a functional disorder of Cl inhibitor or low Cl-inhibitor protein. Dental treatment and oral surgery in patients with HAE can trigger lifethreatening laryngeal edema. However, such episodes of edema can be prevented by appropriate drug therapy.<BR>A 46-year-old man with HAE was referred to our hospital because of facial swelling and abdominal pain. The patient ws admitted and given tranexamic acid. After symptoms improved, he received tooth extraction and cystectomy under local anesthesia. Because we performed minimally invasive surgery and administered tranexamic acid and Cl inhibitor concentration perioperatively, no edema occurred. The patient did not require intubation or tracheotomy.
日本口腔外科学会雑誌 51(5), 260-263, 2005-05-20
Japanese Society of Oral and Maxillofacial Surgeons