原発不明頸部リンパ節転移巣を有する癌患者に認められたUFT誘発 remitting seronegative symmetrical synovitis with pitting edema (RS 3 PE) の1例 A case of remitting seronegative symmetrical synovitis with pitting edema (RS3PE) induced by UFT in a patient with metastatic foci of unknown origin
We encountered a patient in whom remitting seronegative symmetrical synovitis with pitting edema (RS3PE) developed after treatment with UFT. A 64-year-old man who had cervical and lung metastases of unknown origin was treated with docetaxel hydrate, cisplatin, and 5-fluorouracil. Subsequently, the patient received UFT at a dose of 300 mg/day. Shortly after starting treatment with UFT, symmetrical pitting edema developed in the dorsum of the hands and feet. Since the results of immunological examination were consistently negative for rheumatoid factor, the patient was given a diagnosis of RS3PE. The symptoms of RS3PE markedly improved after the withdrawal of UFT and the start of steroid therapy. The findings suggested that UFT may be related to the development of RS3PE.
日本口腔外科学会雑誌 51(3), 148-151, 2005-03-20
Japanese Society of Oral and Maxillofacial Surgeons