術後長期にわたりインターロイキン‐2を投与した乳腺原発血管肉腫の1例

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タイトル別名
  • ANGIOSARCOMA OF THE BREAST-REPORT OF A CASE WITHOUT EVIDENCE OF RECURRENCE SIX YEARS AFTER OPERATION-

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Primary angiosarcoma of the breast is a rare disease, accounting only for 0.04% of all malignant breast tumors. This paper describes a patient with angiosarcoma of the breast administered interleukin-2 (IL-2) for two years as an adjuvant therapy and the patient has no evidence of recurrent disease for six years after the operation to date. A 32-year-old woman was seen at our hospital because of a mass of the right breast. The right breast tumor was 8.5cm in size, and elastic hard in consistency. On ultrasonography and cytology, hemangioma or angiosarcoma were suspected, and an incisional biopsy of the tumor was performed. Histlogically it was angiosarcoma. Consequently a modified radical mastectomy and axillary dissection were performed. The patient received an adjuvant therapy (interleu-kin-2, 400 thousands JRU/2 weeks×2 years), and has no evidence of recurrent disease for six years. According to the literalure review, 86 cases of angiosarcoma of the breast have been reported in Japan.

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