Human heme oxygenase-1 deficiency: A lesson on serendipity in the discovery of the novel disease

• Koizumi, Shoichi

抄録

金沢大学大学院医学系研究科血管病態制御学

The first case of human heme oxygenase (HO)-1 deficiency was reported by Yachie et al. at our laboratory in the Department of Pediatrics, Angiogenesis and Vascular Development, Kanazawa University Graduate School of Medical Science, in 1999. In the present paper I would like to review this novel disease. Our studies into HO-1 deficiency were called by us 'Kanazawa version Project X'. From the story of our successful discovery we have learned that serendipity is a very important spiritual factor. Serendipity is the making of fortunate and unexpected discoveries by chance (from its possession by the heroes in the Persian fairy tale The Three Princes of Serendip). © 2007 Blackwell Publishing Asia.

収録刊行物

• Pediatrics International

  Pediatrics International 49 125-132, 2007-04-01

  Blackwell Publishing

キーワード

• Bilirubin
• Carbon monoxide
• Heme
• Heme oxygenase
• Serendipity

詳細情報

• CRID: 1050282810924823168
• NII論文ID: 10019494194
• NII書誌ID: AA11320483
• ISSN: 13288067
• Web Site: http://hdl.handle.net/2297/6757
• Web Site: https://search.jamas.or.jp/link/ui/2008000029
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
  • IRDB
  • CiNii Articles