Dendritic Cells-Nature and Classification

• Sato Katsuaki

  Laboratory for Dendritic Cell Immunobiology, Research Center for Allergy and Immunology, RIKEN Yokohama Institute

• Fujita Shigeharu

  Laboratory for Dendritic Cell Immunobiology, Research Center for Allergy and Immunology, RIKEN Yokohama Institute

抄録

Dendritic cells (DCs) are antigen (Ag)-presenting cells (APCs) characterized by a unique capacity to stimulate naïve T cells and initiate primary immune responses. Recent studies suggest that DCs also play critical roles in the induction of central and peripheral immunological tolerance, regulate the types of T cell immune responses, and function as sentinels in innate immunity against microbes. The diverse functions of DCs in immune regulation depend on the heterogeneity of DC subsets and their functional plasticity. Here we review recent progress in our understanding of the nature and classification of DCs.<br>

収録刊行物

• Allergology International

  Allergology International 56 (3), 183-191, 2007

  一般社団法人日本アレルギー学会

キーワード

• Dendritic cells
• Development
• Functional plasticity
• Immune response
• Lineage
• Subset heterogeneity

詳細情報

• CRID: 1390001204633486464
• NII論文ID: 10019815071
• NII書誌ID: AA11091750
• DOI: 10.2332/allergolint.r-06-139
• COI: 1:STN:280:DC%2BD2srgslCluw%3D%3D
• ISSN: 14401592
• ISSN: 13238930
• Web Site: http://api.elsevier.com/content/article/PII:S1323893015308649?httpAccept=text/xml
• Web Site: http://api.elsevier.com/content/article/PII:S1323893015308649?httpAccept=text/plain
• Web Site: https://search.jamas.or.jp/link/ui/2008127383
• 本文言語コード: en
• データソース種別:
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  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可