A case of juvenile advanced liver cirrhosis due to primary sclerosing cholangitis diagnosed on a gastric varices rupture

DOI Web Site Web Site 20 References
  • Nakazawa Midori
    Department of Internal Medicine, Division of Gastroenterology and Hepatology, Kawasaki Municipal Tama Hospital of St. Marianna University, School of Medicine
  • Nagase Yoshihiko
    Department of Internal Medicine, Division of Gastroenterology and Hepatology, Kawasaki Municipal Tama Hospital of St. Marianna University, School of Medicine
  • Igarashi Gaku
    Department of Internal Medicine, Division of Gastroenterology and Hepatology, Kawasaki Municipal Tama Hospital of St. Marianna University, School of Medicine
  • Fukuda Yasunobu
    Department of Internal Medicine, Division of Gastroenterology and Hepatology, Kawasaki Municipal Tama Hospital of St. Marianna University, School of Medicine
  • Baba Satoshi
    Department of Internal Medicine, Division of Gastroenterology and Hepatology, Kawasaki Municipal Tama Hospital of St. Marianna University, School of Medicine
  • Aida Yoshio
    Department of Pathology, Kawasaki Municipal Tama Hospital of St. Marianna University, School of Medicine
  • Miyawaki Makoto
    Department of Internal Medicine, Division of Gastroenterology and Hepatology, Toyoko Hospital of St. Marianna University, School of Medicine
  • Suzuki Michihiro
    Department of Internal Medicine, Division of Gastroenterology and Hepatology, Kawasaki Municipal Tama Hospital of St. Marianna University, School of Medicine

Bibliographic Information

Other Title
  • 胃静脈瘤破裂により診断された原発性硬化性胆管炎による若年者肝硬変進展例
  • 症例報告 胃静脈瘤破裂により診断された原発性硬化性胆管炎による若年者肝硬変進展例
  • ショウレイ ホウコク イ ジョウミャクリュウ ハレツ ニ ヨリ シンダンサレタ ゲンパツセイ コウカセイ タンカンエン ニ ヨル ジャクネンシャ カンコウヘン シンテンレイ

Search this article

Abstract

We experienced a case of juvenile advanced liver cirrhosis due to primary sclerosing cholangitis (PSC) diagnosed on a gastric varices rupture. A 23 years old man, suffering from type 2 diabetes treated by pharmacotherapy since 12 years old, visited our hospital due to hematemesis. Gastroduodenoscopy revealed esophago-gastric varices arising from middle of the esophagus to the squamocolumnar junction, and blood clots were observed in the stomach. A red plug existed on the cardiac varices. We treated them by endoscopic sclerotherapy (EIS). Abdominal CT showed an irregular surface of the liver, and dilations of intrahepatic bile ducts in both lobes. Splenomegaly and dilatated umblical vein were also recognized. Endscopic retrograde cholangiopancreatography (ERCP) revealed a beaded appearance of the intrahepatic duct. We performed a liver needle biopsy, and found a pseudolobular fomation with ductular bilirubin stasis as well as an onion-skin type periductal fibrosis around interlobular bile ducts in portal areas. Enentually we diagnosed him as PSC on the basis of these findings. Despite his young age, he developed type 2 diabetes and advanced liver cirrhosis with portal hypertension due to PSC. Hence we should carefully follow him with consideration of liver transplantation as a treatment option.<br>

Journal

  • Kanzo

    Kanzo 48 (9), 446-451, 2007

    The Japan Society of Hepatology

References(20)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top