Clinical Usefulness of [18F]FDG-PET for Diagnosis of Gastric Cancer,Duodenal Ampullary Cancer and GIST(Gastrointestinal Stromal Tumor)—An Analysis Based on Multi-center Questionnaire Survey—

• TORIZUKA Tatsuo

  Positron Medical Center, Hamamatsu Medical Center

• ITO Kengo

  National Center for Geriatrics and Gerontology

• TORIZUKA Kanji

  Health Research Foundation

Bibliographic Information

Other Title

• 胃癌,十二指腸乳頭部癌,GIST(消化管間葉系腫瘍)の診断における[18F]FDG-PETの臨床的有用性－多施設アンケート調査による検討－
• イガン ジュウニシチョウ ニュウトウブ ガン GIST ショウカカン カンヨウケイ シュヨウ ノ シンダン ニ オケル 18F FDG PET ノ リンショウテキ ユウヨウセイ タシセツ アンケート チョウサ ニ ヨル ケントウ

Abstract

Multi-center survey has been conducted to evaluate a diagnostic accuracy of positron emission tomography using fluorine-18-fluorodeoxyglucose (FDG-PET) for gastric cancer (n=173), duodenal ampullary cancer (n=10), and GIST (gastrointestinal stromal tumor, n=15). For the diagnosis of gastric cancer, FDG-PET was superior in47.4% (82/173), similar in 45.1% (78/173) and inferior in7.5% (13/173), as compared to conventional morphological imaging modalities such as X-ray CT and MRI. FDG-PET was superior in20% (2/10), similar in70% (7/10) and inferior in10% (1/10) for the diagnosis of duodenal ampullary cancer, and was superior in40% (6/15), similar in46.7% (7/15) and inferior in13.3% (2/15) for the diagnosis of GIST, as compared to the conventional imaging modalities. FDG-PET was highly useful for the detection of primary tumor and moderately useful for the diagnosis of metastatic and recurrent diseases. The diagnostic result was better for primary tumor probably because most of patients had advanced gastric cancers. In patients with suspected metastasis or recurrence, FDG-PET was able to detect foci of diseases, which were not evident by morphological imaging modalities. Thus, FDG-PET may have a potential to afford important information for the management of such patients and yield cost-effectiveness by obviating unnecessary surgery.

Journal

• RADIOISOTOPES

  RADIOISOTOPES 57 (1), 25-31, 2008

  Japan Radioisotope Association

Keywords

• [<SUP>18</SUP>F]FDG-PET
• multi-center survey
• gastric cancer
• duodenal ampullary cancer
• gastrointestinal stromal tumor

Details

• CRID: 1390282679134153344
• NII Article ID: 10020156593
• NII Book ID: AN00351589
• DOI: 10.3769/radioisotopes.57.25
• ISSN: 18844111
• ISSN: 00338303
• NDL BIB ID: 9341796
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I9341796
• Web Site: http://www.jstage.jst.go.jp/article/radioisotopes/57/1/57_1_25/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2008120519
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed