Ｌ‐アラビノース摂取による骨格筋線維組成の変化

• 菊沢 歩

  神戸女子大学家政学部

• 田中 紀子

  神戸女子大学家政学部

• 市川 みね子

  財団法人東京都老人総合研究所

• 宮坂 京子

  財団法人東京都老人総合研究所

書誌事項

タイトル別名

• Effects of L-Arabinose on Skeletal Muscle Fiber Composition
• L アラビノース セッシュ ニ ヨル コッカクキン センイ ソセイ ノ ヘンカ

抄録

As L-arabinose is known to selectively inhibit intestinal sucrase activity, it may improve the obesity caused by excess sucrose ingestion. The effects of L-arabinose on energy expenditure and muscle fiber composition were studied using Otsuka Long Evans Tokushima Fatty (OLETF) rats that were fed either a 20% sucrose diet (C) or a 20% sucrose diet containing 1.5% L-arabinose (A) for 21 weeks. At 29 weeks of age, the abdominal adipose tissue weight and cell size were increased in group C, while the increase of weight and cell size were significantly inhibited in group A. L-arabinose also significantly suppressed the increase of blood glucose at 2h after glucose administration. The energy percentage of fat consumed in group A increased by 12.8% when estimated by RQ. The number of type I fibers was significantly increased in the rectus lemons muscle, which-like many other skeletal muscles-is composed of mixed type I and II fibers. These results suggest that L-arabinose is effective for changing the skeletal muscle fiber composition from predominantly glycolytic to oxidative, thus inhibiting the increment of abdominal adipose tissue. Such an altered muscle fiber ratio could improve type 2 diabetes mellitus.

収録刊行物

• 日本栄養・食糧学会誌

  日本栄養・食糧学会誌 58 (2), 51-57, 2005

  公益社団法人 日本栄養・食糧学会

キーワード

• L-アラビノース
• 糖尿病
• 内臓脂肪
• 筋線維組成

詳細情報

• CRID: 1390282681270607232
• NII論文ID: 10020369621
• NII書誌ID: AN00311992
• DOI: 10.4327/jsnfs.58.51
• ISSN: 18832849
• ISSN: 02873516
• ISSN: http://id.crossref.org/issn/00346659
• NDL書誌ID: 7324031
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I7324031
• Web Site: https://search.jamas.or.jp/link/ui/2005202957
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN
• 抄録ライセンスフラグ: 使用不可