The Roles of Vitamin A for Cytoplasmic Maturation of Bovine Oocytes

• IKEDA Shuntaro

  Livestock Farm, Graduate School of Agriculture, Kyoto University

• KITAGAWA Masayuki

  Livestock Farm, Graduate School of Agriculture, Kyoto University

• IMAI Hiroshi

  Livestock Farm, Graduate School of Agriculture, Kyoto University Laboratory of Reproductive Biology, Graduate School of Agriculture, Kyoto University

• YAMADA Masayasu

  Laboratory of Reproductive Biology, Graduate School of Agriculture, Kyoto University

書誌事項

タイトル別名

• Roles of Vitamin A for Cytoplasmic Maturation of Bovine Oocytes

抄録

Vitamin A is one of the micronutrients which have been implicated in cattle reproduction. In cattle, ingested vitamin A, mainly as β-carotene (BC) from forages and retinol ester from formula feed, is metabolized and transported to the oocytes and cumulus-granulosa cells in ovarian follicles through binding to various interacting molecules. The active form of vitamin A, retinoic acid (RA), functions as a regulator of gene expression in these targets. Early research showed the positive effects of vitamin A supplementation on bovine fertility in artificial insemination, and several studies on effects of vitamin A metabolites used in other artificial reproductive techniques (ART), including superovulation, ovum pick up, and in vitro maturation culture have provided evidence for the specific roles of vitamin A in oocyte cytoplasmic maturation (acquisition of developmental competence of oocytes during their meiotic maturation period for the embryonic development after fertilization). BC may enhance cytoplasmic maturation by its antioxidant properties which cannot be replaced by RA. Furthermore, RA may promote cytoplasmic maturation of bovine oocytes via its modulatory effects on the gene expression of gonadotrophin receptors, midkine, cyclooxygenase-2, and nitric oxide synthase in cumulus-granulosa cells.<br>

収録刊行物

• Journal of Reproduction and Development

  Journal of Reproduction and Development 51 (1), 23-35, 2005

  公益社団法人 日本繁殖生物学会

キーワード

• Vitamin A
• Cattle
• Oocyte
• Cytoplasmic maturation

詳細情報

• CRID: 1390282681312814336
• NII論文ID: 10020372298
• NII書誌ID: AA10936678
• DOI: 10.1262/jrd.51.23
• ISSN: 13484400
• ISSN: 09168818
• NDL書誌ID: 7263406
• PubMed: 15750294
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I7263406
• Web Site: http://www.jstage.jst.go.jp/article/jrd/51/1/51_1_23/_pdf
• 本文言語コード: en
• データソース種別:
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  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
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