書誌事項
- タイトル別名
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- Effects of Dietary γ-Linolenic Acid on Insulin- Responsive Glucose Transporter (GLUT 4) Protein Expression in Pigs
- Effects of Dietary ガンマーLinolenic Acid o
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Recent study has revealed that dietary γ-linolenic acid (GLA, 18:3(n-6)) reduces body fat contents and enhances activities of liver carnitine palmitoyltransferase and peroxisomal β-oxidation. However, we considered that GLA might affect not only enzymes involved in lipid metabolism but also in glucose metabolism. Insulin-responsive glucose transporter (GLUT 4) represents the rate-limiting step in glucose metabolism and considered to have an important role for energy accumulation. Present study was conducted to determine whether GLA affects GLUT 4 protein expression in pig tissues. Nine pigs (70kg, castrated males) were allotted to two groups and fed either 90g/day GLA-enriched oil (n=5) or soybean oil (n=4, control) with a formula diet for 6 weeks. The GLA-enriched oil contained 25.3% GLA of fatty acids. The GLUT 4 protein levels were determined by immunoblotting using GLUT 4 antiserum and an enhanced chemiluminescent (ECL) system. GLA treatment significantly reduced GLUT 4 protein contents in M. vastus lateralis compared with control (P<0.05). The GLUT 4 contents in the GLA treatment group also tended to be lower in M. longissimus dorsi and subcutaneous white adipose tissue. These results show that nutritional control may affect GLUT 4 expression in pig tissues.
収録刊行物
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- 日本畜産学会報
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日本畜産学会報 69 (4), 347-354, 1998
公益社団法人 日本畜産学会
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詳細情報 詳細情報について
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- CRID
- 1390282680172896640
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- NII論文ID
- 10021726341
- 10020395566
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- NII書誌ID
- AN00195188
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- ISSN
- 18808255
- 00215309
- 1346907X
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- NDL書誌ID
- 4471126
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可