Analysis of drug compliance in adult patients with bronchial asthma. Based on questionnaire surveys in Niigata Prefecture, Japan

  • Hasegawa Takashi
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences
  • Suzuki Eiich
    Department of General Medicine, Niigata University Medical and Dental Hospital
  • Koya Toshiyuki
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences
  • Akazawa Kouhei
    Division of Medical Information Science, Niigata University Medical and Dental Medical Hospital
  • Sakagami Takurou
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences
  • Toyabe Shinich
    Division of Medical Information Science, Niigata University Medical and Dental Medical Hospital
  • Koyanagi Kumiko
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences
  • Kawano Kenji
    Department of Pharmacy, Niigata University of Pharmacy and Applied Life Sciences
  • Haraguchi Michihiko
    Division of Respiratory Medicine, Niigata City General Hospital
  • Toyama Joji
    Division of Respiratory Medicine, Keinan General Hospital
  • Arakawa Masaaki
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences
  • Yoshizawa Hirohisa
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences
  • Satoh Hiroshi
    Department of Pharmacy, Niigata University Medical and Dental Hospital
  • Gejyo Fumitake
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences

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タイトル別名
  • Analysis of Drug Compliance in Adult Patients with Bronchial Asthma
  • Based on Questionnaire Surveys in Niigata Prefecture, Japan

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BACKGROUND: In Japan, there have been few reports about drug compliance, which is an important determinant of effectiveness, in the management of bronchial asthma patients. To clarify drug compliance and its relationship with various aspects of asthma management, a questionnaire survey was performed on asthmatic patients and their pharmacists.<BR>METHODS: This survey was carried out, from October to November in 2001. The subjects were limited to the regular inhaled corticosteroid (ICS) users, and were restricted to patients whose medication had not been changed for at least 6 months before the survey. The questionnaires inquired about asthma status, various factors that have been reported to be associated with drug compliance and asthma management. Patients' pharmacists were asked about prescribed medications and drug compliance based on the pharmaceutical records.<BR>RESULTS: Completed questionnaires were received from 610 patients. ICS compliance was not lower than that of anti-allergic drug but lower than that of oral sustained-released theophylline (OSRT) . Multiple regression analysis revealed a significant correlation between ICS and OSRT compliance.<BR>CONCLUSION: These results might suggest that OSRT could improve patient's compliance to drug therapy through its bronchodilatory effect, thus resulting in better compliance to ICS. If this were the case, OSRT would play an important role in asthma management.

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