Acetyl chloride-mediated synthesis of trans-2-〔(Diethoxyphosphorylamino)alkyl〕-4-aryl-5,5-dimethyl-1,3,2λ[5]-dioxaphosphorinane-2-oxide

• Zhiwei Miao

• Jianfeng Zhang

• Zhanwei Cui

Bibliographic Information

Other Title

• Acetyl chloride mediated synthesis of trans 2 Diethoxyphosphorylamino alkyl 4 aryl 5 5 dimethyl 1 3 2 l 5 dioxaphosphorinane 2 oxide

Abstract

N-Phosphoramino-protected six-membered cyclic α-aminophosphonates trans-2-[(diethoxyphosphorylamino)alkyl]-4-aryl-5,5-dimethyl-1,3,2λ5-dioxaphosphorinane-2-oxide 4a–4l were synthesized with the help of acetyl chloride. 31P NMR was used to trace the reaction process. A possible reaction mechanism was proposed and the stereochemistry of the title compounds was studied. In order to confirm the structure of 4, products 4f and 4k were recrystallized and determined by X-ray diffraction analysis.

Journal

• Bulletin of the Chemical Society of Japan

  Bulletin of the Chemical Society of Japan 81 (5), 630-635, 2008

  Tokyo : Chemical Society of Japan

Keywords

• General Chemistry

Details

• CRID: 1521417755501321984
• NII Article ID: 10021075624
• NII Book ID: AA00580132
• ISSN: 00092673
• ISSN: 13480634
• DOI: 10.1246/bcsj.81.630
• NDL BIB ID: 9489837
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I9489837
• Web Site: https://academic.oup.com/bcsj/article-pdf/81/5/630/56270135/bcsj.81.630.pdf
• Text Lang: en
• NDL Source Classification:
  • ZP1(科学技術--化学・化学工業)
• Data Source:
  • NDL
  • Crossref
  • CiNii Articles