<i>C</i> 2-Symmetric Chiral Malonamides for Asymmetric Michael Reaction

• Sung-Ji Kim

  Research Institute of Pharmaceutical Science and College of Pharmacy, Seoul National University

• Kyoungyim Lee

  Research Institute of Pharmaceutical Science and College of Pharmacy, Seoul National University

• Sang-sup Jew

  Research Institute of Pharmaceutical Science and College of Pharmacy, Seoul National University

• Hyeung-geun Park

  Research Institute of Pharmaceutical Science and College of Pharmacy, Seoul National University

• Byeong-Seon Jeong

  College of Pharmacy, Yeungnam University

抄録

Described is the design and preparation of chiral C2-symmetric malonamides and their application to asymmetric conjugate addition to enone. The mechanism of partial racemization observed in the course of hydrolysis–decarboxylation step is also elucidated.

収録刊行物

• Chemistry Letters

  Chemistry Letters 37 (4), 432-433, 2008-03-08

  Oxford University Press (OUP)

キーワード

• General Chemistry

詳細情報

• CRID: 1360283694087852800
• NII論文ID: 10021079569
• NII書誌ID: AA00603318
• DOI: 10.1246/cl.2008.432
• ISSN: 13480715
• ISSN: 03667022
• Web Site: https://academic.oup.com/chemlett/article-pdf/37/4/432/55596955/cl.2008.432.pdf
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