C_2-Symmetric Chiral Malonamides for Asymmetric Michael Reaction
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Described is the design and preparation of chiral <I>C</I><SUB>2</SUB>-symmetric malonamides and their application to asymmetric conjugate addition to enone. The mechanism of partial racemization observed in the course of hydrolysis–decarboxylation step is also elucidated.
- Chemistry Letters
Chemistry Letters 37(4), 432-433, 2008-04-05
The Chemical Society of Japan