An Unusual Iodinated 5'-Deoxyxylofuranosyl Nucleoside from an Okinawan Ascidian, Diplosoma sp.
An unusual nucleoside, 4-amino-7-(5′-deoxy-β-<small>D</small>-xylofuranosyl)-5-iodopyrrolo[2,3-<I>d</I>]pyrimidine (<B>1</B>), was isolated from an ascidian, <I>Diplosoma</I> sp., and its structure was successfully determined by spectroscopic and chemical analysis. The known didemnenones <B>2</B>–<B>5</B> were also isolated. Compound <B>1</B> was found to inhibit the division of fertilized sea urchin eggs.
- Chemistry letters
Chemistry letters 37(4), 448-449, 2008-04-05
The Chemical Society of Japan