Vanadium-catalyzed Asymmetric Transcyanation of Aliphatic Aldehydes with Acetone Cyanohydrin
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The vanadium(V)(salalen) complex prepared in situ from the corresponding vanadium(IV) complex <B>4</B> under aerobic conditions was found to be an excellent catalyst for asymmetric transcyanation of aliphatic aldehydes with acetone cyanohydrin as the cyanide source, showing high enantioselectivity of 91–95% ee.
- Chemistry Letters
Chemistry Letters 37(5), 502-503, 2008-05-05
The Chemical Society of Japan