Highly Efficient Method for the Synthesis of Carboxamides from Carboxylic Acids and Amines Using Pyridine-3-sulfonyl Chloride (3-PSC)
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The use of pyridine-3-sulfonyl chloride (3-PSC) in dehydrating condensation was investigated. This novel reagent was successfully employed as a mild dehydrating reagent for preparing various carboxamides in good to excellent yields from the corresponding carboxylic acids and amines.
- Chemistry Letters
Chemistry Letters 37(5), 506-507, 2008-05-05
The Chemical Society of Japan