Glucose Responsive Two-step Release of Hydrogel-immobilized Protein

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抄録

We designed a two-step-release system that enables protein release from hydrogel in response to glucose. In the system, one of the heterodimeric coiled-coil forming peptides was initially fixed to a hydrogel via a boronate–diol interaction. The peptide was specifically released from the hydrogel by externally incoming glucose. As a result, a protein immobilized in another hydrogel was librated owing to the displacement by the peptide at its hydrogel-bound coiled-coil moiety.

収録刊行物

  • Chemistry letters  

    Chemistry letters 37(6), 582-583, 2008-06-05 

    The Chemical Society of Japan

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各種コード

  • NII論文ID(NAID)
    10021080928
  • NII書誌ID(NCID)
    AA00603318
  • 本文言語コード
    ENG
  • 資料種別
    SHO
  • ISSN
    03667022
  • データ提供元
    CJP書誌  J-STAGE 
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