Progress in Rapid Identification and Classification of Bacteria by Mass Spectrometry

  • TERAMOTO Kanae
    Advanced Technology Division, JEOL Ltd.
  • SATO Hiroaki
    Research Institute for Environmental Management Technology, National Institute of Advanced Industrial Science and Technology (AIST)

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  • 質量分析法によるバクテリアの迅速同定・分類法の進歩
  • シツリョウ ブンセキホウ ニ ヨル バクテリア ノ ジンソク ドウテイ ブンルイホウ ノ シンポ

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Abstract

Rapid identification and classification of bacteria by mass spectrometry (MS) have been expected to play important roles in various fields such as food industries, biomedical assays, and environmental analysis. In this review, the historical progress of various mass spectrometric approaches from pyrolysis-MS to matrix-assisted laser desorption/ionization (MALDI)-MS and their features are outlined. Then, the details of the development of bacterial analysis based on MALDI-MS are discussed. Among these, recent progress in MALDI-MS-based identification and classification of bacteria using ribosomal proteins as biomarkers is described in brief.

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