Considerations Regarding the Importance of <i>In Vivo</i> Data for the Development of an Alternative to Conventional Skin Irritation Testing

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Regarding possible alternatives to skin irritation testing using animals, I will comment on the importance of comparing in vivo data with in vitro data from the viewpoint of the specific purposes and needs of product testing. I recommend an alternative method using the results of occluded human patch tests, without of the need for animal testing.

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