IPMCの細胞毒性試験および質量分析 [in Japanese] Cytotoxicity Test and Mass Spectrometry of IPMC [in Japanese]
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Ionic polymer-metal composite (IPMC) is a promising material in biomedical actuators and sensors because IPMC is soft and flexible, leading to the safety of the device itself. The purpose of this study is to investigate the biocompatibility of IPMC by <i>in vitro</i> experiments, in order to evaluate the applicability in biomedical fields. In addition to an IPMC specimen prepared by the conventional "impregnation-reduction method" using cationic gold complexes and reducing agents, two specimens were prepared by processes in addition to that used for the conventional IPMC specimen. One specimen was reduced in Na<sub>2</sub>SO<sub>3</sub> solution and another specimen was cleaned in H<sub>2</sub>O<sub>2</sub> solution. Colony-forming test using Chinese hamster V79 cells shows high cytotoxicity of all IPMC specimens. Examination of direct inlet mass spectrometry (DI-MS) revealed that the peak intensity of gold complex (particularly, <i>m</i>/<i>z</i>=180) was different from that of Nafion film. Monitoring the peak at <i>m</i>/<i>z</i>=180 showed a remnant with the structure of phenanthroline in IPMC specimens which were not cleaned in H<sub>2</sub>O<sub>2</sub> solution.
- IEEJ Transactions on Electronics, Information and Systems
IEEJ Transactions on Electronics, Information and Systems 128(7), 1029-1035, 2008-07-01
The Institute of Electrical Engineers of Japan