パルス電解法により作製したチタニア／水酸アパタイト複合膜の骨伝導性評価

• 黒田 健介

  名古屋大学大学院工学研究科マテリアル理工学専攻材料工学分野

• 志津 裕信

  名古屋大学大学院工学研究科マテリアル理工学専攻材料工学分野

• 市野 良一

  名古屋大学大学院工学研究科マテリアル理工学専攻材料工学分野

• 興戸 正純

  名古屋大学大学院工学研究科マテリアル理工学専攻材料工学分野

• 関 あずさ

  ハムリー株式会社

書誌事項

タイトル別名

• Osteoconductivity of Titania/Hydroxyapatite Composite Films Formed Using Pulse Electrolysis
• パルス デンカイホウ ニ ヨリ サクセイシタ チタニア スイサン アパタイト フクゴウマク ノ コツ デンドウセイ ヒョウカ

抄録

  Titania (TiO₂)/hydroxyapatite (HAp) composite films were prepared on commercial pure titanium rods (2 mm in diameter, 5 mm in length) by anodic-cathodic pulse electrolysis in an aqueous solution consisting of 0.3 mM Ca(H₂PO₄)₂ and 0.7 mM CaCl₂ and pH=5.5. The electrolysis was carried out in an autoclave at 120°C for 30 min. using +8.7 V vs. Ag/AgCl sat. KCl as the anodic potential and -9.3 V as the cathodic potential, and changing the electrolysis cycle (60~600 s) and duty ratio. We obtained TiO₂/HAp composite films in which fine HAp particles were uniformly dispersed on a thin TiO₂ layer. The coated rods were implanted in the tibiae of 10-week-old male rats. The constructs were retrieved 14 d postimplantation and examined for new bone formation and tissue response in the cancellous and cortical bone. They were compared with HAp-coated titanium rods, TiO₂-coated rods (anodizing in an aqueous solution), TiO₂/HAp-coated rods formed by the high temperature oxidization of specimens coated with HAp by cathodic electrolysis, and uncoated titanium rods. Fourteen days after implantation, new bone had formed on all the coated samples (HAp, TiO₂, and TiO₂/HAp) and noncoated titanium rods in the cancellous bone and cortical bone. In particular, TiO₂/HAp composite films prepared by pulse electrolysis had very high osteoconductivity in the part of cortical bone, which resulted from a synergistic effect of HAp and TiO₂ on the bioactivity.<br>

収録刊行物

• 日本金属学会誌

  日本金属学会誌 72 (5), 383-387, 2008

  公益社団法人 日本金属学会

キーワード

• hydroxyapatite
• titania
• composite coating
• pulse electrolysis
• anodizing
• hydroprocess

詳細情報

• CRID: 1390001206479816832
• NII論文ID: 10021150405
• NII書誌ID: AN00187860
• DOI: 10.2320/jinstmet.72.383
• COI: 1:CAS:528:DC%2BD1cXnvVentrk%3D
• ISSN: 18806880
• ISSN: 24337501
• ISSN: 00214876
• NDL書誌ID: 9514484
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I9514484
• Web Site: https://www.jstage.jst.go.jp/article/jinstmet/72/5/72_5_383/_pdf
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN
• 抄録ライセンスフラグ: 使用不可