高圧下へのタンパク質の適応 Protein Adaptation to High-Pressure Environments

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著者

    • 加藤 千明 KATO Chiaki
    • 独立行政法人海洋研究開発機構 極限環境生物圏研究センター Extremobiosphere Research Center, Japan Agency for Marine-Earth Science and Technology (JAMSTEC)

抄録

Studies of pressure-adapted (piezophilic) protein have lagged behind the investigation of other extremophilic proteins, however the recent characterization of proteins from deep-sea organisms has substantially accelerated the field. Recent experiments on proteins from deep-sea sources have contributed to our understanding of protein adaptation to high pressure. These studies have also complemented previous work that had investigated the effect of pressure on the activity and stability of "normal", unadapted proteins. Together this research has lead to the conclusion that volume changes due to the hydration effects of exposed side chains and large internal cavities drive protein unfolding under high pressure.

収録刊行物

  • 高圧力の科学と技術 = The Review of high pressure science and technology  

    高圧力の科学と技術 = The Review of high pressure science and technology 18(2), 128-132, 2008-05-20 

    The Japan Society of High Pressure Science and Technology

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各種コード

  • NII論文ID(NAID)
    10021153494
  • NII書誌ID(NCID)
    AN10452913
  • 本文言語コード
    JPN
  • 資料種別
    REV
  • ISSN
    0917639X
  • NDL 記事登録ID
    9536453
  • NDL 雑誌分類
    ZP1(科学技術--化学・化学工業)
  • NDL 請求記号
    Z17-1589
  • データ提供元
    CJP書誌  NDL  J-STAGE 
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