A Multiphase Microfluidic System for Micro Droplet Formation and Its Application

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Other Title
  • プラズモニクス／バイオＭＥＭＳ　　混相流マイクロ流体システムを用いた微小マイクロ液滴の生成と応用
  • 混相流マイクロ流体システムを用いた微小マイクロ液滴の生成と応用
  • コンソウリュウ マイクロ リュウタイ システム オ モチイタ ビショウ マイクロ エキテキ ノ セイセイ ト オウヨウ

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Abstract

Micro droplets produced from the introduction of immiscible fluids of organic phase and water phase are useful for a wide range of applications, especially in the field of chemistry and biochemistry. Smaller micro droplets in the microfluidic system increase the efficiencies of chemical reaction and extraction in liquid-liquid interfaces. In order to realize high generation rate of the uniform oil-in-water droplets, we invented the multi-stage divergence system. The droplet generation rate was achieved by the uniform micro fluidic separation up to 16 micro droplets from one droplet. The maximum generation rate was 1760 droplets/s and the deviationof their diameters was smaller than 3%. The generation rate and diameter were well controlled by the flow rates of water phase and organic phase. We also developed the fabrication of nano-porous polymer microcapsules using self-assembly of the block copolymers in the multipahse microfluidic system. The spherical microcapsule was successfully fabricated with the polymer thickness of 0.5∼1.5 μm and nano pores.

Journal

  • Hyomen Kagaku

    Hyomen Kagaku 29 (6), 356-363, 2008

    The Surface Science Society of Japan

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