DNAを利用したAuナノ微粒子のシーケンシャルセルフアセンブル [in Japanese] DNA Mediated Sequential Self-assembly of Au Nano-particles [in Japanese]
Access this Article
Search this Article
The novel sequential self-assembly process applying hybridization of DNA mediated micro/nano components was proposed and its validity was experimentally verified. In the proposed process, characteristic of DNA, such as hybridization specificity of complementary pairs of single-stranded DNA (ssDNA) into a double-stranded DNA (dsDNA), and its dependence on melting temperature <i>T</i><sub>m</sub>, which can be designed by the base-pair sequence and salt-concentration of surrounding media, was utilized to control the self-assembly sequence of a micro/nano components modified by ssDNA. Au nanoparticles with 15nm diameter were used as components and two pairs complementary DNA with different <i>T</i><sub>m</sub> were prepared. The aggregation of Au nano-particles modified by complementary ssDNA was confirmed at different temperatures with decreasing temperature under <i>T</i><sub>m</sub>. The reversibility of this process was also confirmed by increasing temperature.
- Journal of the Research Association of Powder Technology, Japan
Journal of the Research Association of Powder Technology, Japan 45(3), 156-161, 2008-03-10
The Society of Powder Technology, Japan