パラジウムの分子内転位 [in Japanese] Intramolecular Palladium Migration [in Japanese]
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Specific conversion of C-X bond to C-C bond by palladium-catalyzed reaction has been widely used in organic synthesis. Recently, several groups reported unusual C-C bond formation occurred at a different carbon from which halogen was initially attached. These reaction has been considered to happen through intramolecular migration of palladium before the C-C bond was formed. Larock et al. discovered a set of reaction conditions which enables to switch such migration on or off. Sharp et al. reported stepwise migration of isolated complexes. By focusing on these results, intramolecular palladium migration will be briefly discussed.
- J. Synth. Org. Chem. Jpn.
J. Synth. Org. Chem. Jpn. 66(3), 251-252, 2008-03-01
The Society of Synthetic Organic Chemistry, Japan