Superior Mesenteric Venous Thrombosis: Study of Five Cases

  • Goto Hitoshi
    Division of Organ Transplantation, Reconstruction & Endoscopic Surgery, Tohoku University Hospital
  • Sato Akira
    Division of Organ Transplantation, Reconstruction & Endoscopic Surgery, Tohoku University Hospital
  • Watanabe Tetsuo
    Division of Organ Transplantation, Reconstruction & Endoscopic Surgery, Tohoku University Hospital
  • Hashimoto Munetaka
    Division of Organ Transplantation, Reconstruction & Endoscopic Surgery, Tohoku University Hospital
  • Sugawara Hirofumi
    Division of Organ Transplantation, Reconstruction & Endoscopic Surgery, Tohoku University Hospital
  • Nakano Yoshiyuki
    Division of Organ Transplantation, Reconstruction & Endoscopic Surgery, Tohoku University Hospital
  • Zukeran Tsutomu
    Division of Organ Transplantation, Reconstruction & Endoscopic Surgery, Tohoku University Hospital
  • Serizawa Fukashi
    Division of Organ Transplantation, Reconstruction & Endoscopic Surgery, Tohoku University Hospital
  • Satomi Susumu
    Division of Organ Transplantation, Reconstruction & Endoscopic Surgery, Tohoku University Hospital

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Other Title
  • 上腸間膜静脈血栓症の5症例による臨床的特徴の考察

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Abstract

<p>Superior mesenteric venous thrombosis (SMVT) is an uncommon cause of intestinal ischemia which is associated with a high degree of morbidity and mortality. The development of computed tomography has been making the diagnosis of this disease easier if we can outline this pathological state. We reviewed five SMVT patients in our hospital from 2000 to 2007 and discussed the clinical character. Though laboratory work up showed none of these patients had congenital or acquired thrombophilia, all patient were associated with some pathological states like inflammatory bowel disease, essential thrombocythemia, eosinophilic enteritis and acute pancreatitis which sometimes show hypercoagulability. Four patients showed acute abdomen and three of them underwent emergent operation. Characteristic abdominal findings in acute SMVT were severe abdominal pain with distension, without peritoneal sign at the beginning. Multidetector computer tomography revealed SMVT precisely. As D-dimer level elevated markedly in all acute SMVT patients, this would be helpful when diagnose acute SMVT. All patients were treated with early initiation of anticoagulant therapy especially with unfractionated heparin, whether they underwent further treatment or not. This would be important to minimize SMVT extension.</p>

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