JSAR Outstanding Presentation Award 2006: Heterologous gap junctions between granulosa cells and oocytes in Ayu (Plecoglossus altivelis) : formation and role during luteinizing hormone-dependent acquisition of oocyte maturational competence

DOI Web Site Web Site 参考文献34件
  • YAMAMOTO Yoji
    Department of Marine Biosciences, Tokyo University of Marine Science and Technology
  • YOSHIZAKI Goro
    Department of Marine Biosciences, Tokyo University of Marine Science and Technology

書誌事項

タイトル別名
  • Heterologous Gap Junctions between Granulosa Cells and Oocytes in Ayu (Plecoglossus altivelis): Formation and Role during Luteinizing Hormone-dependent Acquisition of Oocyte Maturational Competence

この論文をさがす

抄録

Gap junctions (GJs) are intercellular channels. Molecules with a molecular weight of 1 kDa or less can pass back and forth between adjacent cells through GJs. Communication between oocytes and the somatic cells that surround them via GJs is known to play key roles to initiate oocyte maturation in many vertebrates. However, little is known of the detailed functions of ovarian GJs during oocyte maturation in fish. The oocyte maturation of fish is induced by a maturation-inducing steroid (MIS). The sensitivity of oocytes to the MIS is known as oocyte maturational competence (OMC) and is induced by luteinizing hormone (LH). However, LH receptors are found on the surface of granulosa cells rather than oocytes. We therefore proposed that the LH signals received by granulosa cells were passed to oocytes via GJs. This review describes current knowledge of the role of GJs between granulosa cells and oocytes during the LH-induced acquisition of OMC in fish.<br>

収録刊行物

参考文献 (34)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ