Immune Enhancing Properties of Safflower Leaf (Carthamus tinctorius) on Chicken Lymphocytes and Macrophages

この論文にアクセスする

この論文をさがす

著者

抄録

Safflower (<I>Carthamus tinctorius</I>) has been used as a traditional medicinal plant to enhance natural immunity and treat cancers. However, limited information exists on the mechanisms responsible for its immune enhancing properties. In this study, the immunostimulatory effects of a methanol extract of safflower leaf were assessed by <I>in vitro</I> lymphocyte proliferation, tumor cell cytotoxicity, and nitric oxide production by cultured chicken macrophages. A crude methanol extract of safflower leaf stimulated spleen lymphocyte proliferation and nitric oxide production, and inhibited the viability of tumor cells significantly greater than medium controls. Sequential gel filtration chromatographic separation of the methanol extract on Sephadex G-25 and Sephacryl S-200 columns resulted in a partially purified preparation that retained the ability to induce lymphoproliferation, tumor killing, and NO production. These results demonstrate for the first time that safflower leaf contains immunostimulatory and anti-tumor component(s) that may be potentially useful as a dietary immunomodulator for poultry.

収録刊行物

  • The journal of poultry science  

    The journal of poultry science 45(2), 147-151, 2008-04-25 

    日本家禽学会

参考文献:  20件

参考文献を見るにはログインが必要です。ユーザIDをお持ちでない方は新規登録してください。

被引用文献:  3件

被引用文献を見るにはログインが必要です。ユーザIDをお持ちでない方は新規登録してください。

各種コード

  • NII論文ID(NAID)
    10021220262
  • NII書誌ID(NCID)
    AA11564513
  • 本文言語コード
    ENG
  • 資料種別
    NOT
  • ISSN
    13467395
  • NDL 記事登録ID
    9469281
  • NDL 雑誌分類
    ZR22(科学技術--農林水産--畜産)
  • NDL 請求記号
    Z54-J694
  • データ提供元
    CJP書誌  CJP引用  NDL  J-STAGE 
ページトップへ