Clinical features and treatments of antiphospholipid syndrome

• KABURAKI Junichi

  Department of Internal Medicine, Tokyo Electric Power Company (TEPCO) Hospital

Bibliographic Information

Other Title

• 抗リン脂質抗体症候群における臨床像と治療

Abstract

  Antiphospholipid antibodies are serological markers of antiphospholipid syndrome (APS). Diversity of so-called antiphospholipid antibodies is well-known. These antibodies are directed against phospholipid binding proteins such as β₂-glycoprotein I and prothrombin as well as against phospholipids such as cardiolipin. Thrombosis and pregnancy morbidity are clinical features of APS. In addition, cardiovascular manifestations, neurological disorders, skin manifestations, renal involvements and thrombocytopenia are reported to be significant in clinical aspects of APS. Anticoagulation therapy and antiplatelet therapy are effective for the secondary prevention of thrombosis in APS.<br>

Journal

• Japanese Journal of Clinical Immunology

  Japanese Journal of Clinical Immunology 31 (3), 152-158, 2008

  The Japan Society for Clinical Immunology

Keywords

• Antiphospholipid antibodies
• Thrombosis
• Pregnancy morbidity
• Aspirin
• Warfarin

Details

• CRID: 1390001204649911936
• NII Article ID: 10021242650
• NII Book ID: AN00357971
• DOI: 10.2177/jsci.31.152
• ISSN: 13497413
• ISSN: 09114300
• Web Site: http://www.jstage.jst.go.jp/article/jsci/31/3/31_3_152/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2008273516
• Text Lang: ja
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed