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- Matsushita Sho
- Department of Allergy and Immunology, Faculty of Medicine, Saitama Medical University
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- Higashi Takehiro
- Department of Allergy and Immunology, Faculty of Medicine, Saitama Medical University
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抄録
Immunomodulators such as lipopolysaccharides (LPS) and forskolin change the nature of dendritic cells (DCs) to induce Th1 and Th2 cells, respectively, thereby designated Th1 or Th2 adjuvants. Recent studies showed that Th17-inducing activity can be carried by certain polysaccharides such as β-glucan derived from Candia albicans. Such activities can be scrutinized by using MLR, cAMP and possibly, differential expression of Notch ligand isoforms. In this review article, we also introduce an effective method to establish human Th17 cell clones and a transcriptome analysis using human Th subpopulations. In vivo relevance to human Th17 responses is discussed.<br>
収録刊行物
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- Allergology International
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Allergology International 57 (2), 135-140, 2008
一般社団法人日本アレルギー学会
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詳細情報 詳細情報について
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- CRID
- 1390001204632088448
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- NII論文ID
- 10021246514
- 130004476966
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- NII書誌ID
- AA11091750
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- ISSN
- 14401592
- 13238930
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- PubMed
- 18427166
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可