Sustained Remission after Rituximab-containing Chemotherapy for Intravascular Large B-cell Lymphoma

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著者

    • NARIMATSU Hiroto
    • Department of Hematology and Oncology, Nagoya University Graduate School of Medicine
    • SHIMADA Satoko
    • Department of Pathology of Biological Response, Nagoya University Graduate School of Medicine
    • ITO Masafumi
    • Department of Pathology, Japanese Red Cross, Nagoya First Hospital
    • KINOSHITA Tomohiro
    • Department of Hematology and Oncology, Nagoya University Graduate School of Medicine
    • MORI Naoyoshi
    • Department of Pathology of Biological Response, Nagoya University Graduate School of Medicine
    • NAOE Tomoki
    • Department of Hematology and Oncology, Nagoya University Graduate School of Medicine

抄録

Intravascular large B-cell lymphoma (IVL) is rare aggressive disseminated lymphoma associated with poor outcomes. Rituximab is a novel molecular agent that can reportedly improve outcomes for patients with diffuse large B-cell lymphoma. However, the safety and efficacy of rituximab in patients with IVL are unclear. A 76-year-old woman was hospitalized due to altered consciousness, fever and respiratory abnormalities. Definitive diagnosis of IVL was obtained following repeated biopsies of bone marrow. The patient received chemotherapy consisting of cyclophosphamide, vincristine, doxorubicin, prednisolone, and rituximab (R-CHOP), and achieved complete remission after 3 courses of treatment. She has remained in complete remission for over 3 years after diagnosis. This report suggests that rituximab-containing regimens could be safe and effective for elderly patients with IVL. [<I>J Clin Exp Hematopathol 48(1) : 25-28, 2008</I>]

収録刊行物

  • Journal of clinical and experimental hematopathology  

    Journal of clinical and experimental hematopathology 48(1), 25-28, 2008-05-01 

    The Japanese Society for Lymphoreticular Tissue Research

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各種コード

  • NII論文ID(NAID)
    10021246736
  • NII書誌ID(NCID)
    AA11556796
  • 本文言語コード
    ENG
  • 資料種別
    NOT
  • ISSN
    13464280
  • データ提供元
    CJP書誌  CJP引用  J-STAGE 
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